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I already have that from the MCAS and thyroid. Most clinicians, including myself, now believe that Mast Cell Activation Disorder is a more accurate description of what patients with so-called histamine intolerance are suffering from. Can poor sleep impact your weight loss goals? This can be especially helpful in treating antibiotic resistant infections, or people who are allergic to specific antibiotics. Symptoms of histamine intolerance may include changes in blood pressure, hives, itchy skin, welts, anxiety, irritability, gas, bloating, headaches, diarrhea. I also restarted Chlorophyll which is providing Copper. Get to the root of the problem. Is the Singulair helping you? So I get all my meds from my regular dr. You dont have to go to an allergist to get a diagnosis of MCAS a regular dr is just fine. Mucuna pruriens, also known as velvet bean, is a natural source of the dopamine precursor L-DOPA, a strong inhibitor of histidine decarboxylase (HDC) in cell studies. We had mold removed from our home, she was bit on the head by a deer tick, and she also had a very bad reaction to vaccines. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. I hate spam, too. diarrhea. In one study, 1 g of vitamin C directly decreased histamine in all 11 volunteers that it was given to; as vitamin C levels went back down, histamine levels increased. Chicken with new potatoes, broccoli, and green beans. Can chemo do something to the mast cells to cause these issues? All Rights Reserved | Privacy Policy | Terms & Conditions | Return Gurantee & Shipping Info | Do Not Sell My Personal Information. Smoked fish and certain species of fish including mackerel, mahi-mahi, tuna, anchovies, sardines, Vinegar-containing foods: pickles, mayonnaise, olives, Fresh fruits: mango, pear, watermelon, apple, kiwi, cantaloupe, grapes, Fresh vegetables (except tomatoes, spinach, and eggplant), Gluten-free grains*: rice, quinoa, corn, millet, amaranth, teff. The wine they drink though is made with truly natural, unadulterated ingredients. For optimal results, remove high histamine foods for 30 days. Any clue as to why? Can wheat allergics tolerate wheatgrass? These hormones make up the flight or fight mechanism you may have heard about. I have experienced two memorable reactions which I believe were near anaphylaxis attacks: nausea, rapid pulse, overheating, muscle weakness and pre-syncope triggered by heat and sunlight. However, the studies listed below should not be interpreted as supportive of any health benefit. You might be familiar with histamine in relation to your immune system. Mastattack and healing histamine deal specifically with mast cell related things and inspire.com is an online community for people with rare diseases like mastocytosis and MCAS (MCAS isnt rare anymore unfortunately). MyLabsForLife.com. We are addressing gene mutations with methylation and detoxification. I cant take T4. Note, however, that chocolate also contains some histamine, and researchers suspect that it may encourage histamine release. What foods should people eat with ulcerative colitis? It stabilizes mast cells and relaxes muscles in the lungs comparably to two common asthma drugs, sodium cromoglycate and beclomethasone [1, 2, 3, 4, 5]. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Complementary Medicine / Alternative Medicine, https://link.springer.com/article/10.1007/s13562-015-0309-7, https://pdfs.semanticscholar.org/46b8/ee98f7856d53c40688fdaa17eef6b9d46207.pdf?_ga=2.125579338.177931791.1571231643-1662965488.1571067929, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534514/, https://www.tandfonline.com/doi/full/10.1080/09168451.2015.1006567, https://www.beyondceliac.org/gluten-free-diet/is-it-gluten-free/wheatgrass/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527060/, https://plants.usda.gov/plantguide/pdf/pg_pasm.pdf, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947926/, https://onlinelibrary.wiley.com/doi/abs/10.1111/1750-3841.14224, http://www.jdrr.org/article.asp?issn=2348-2915;year=2015;volume=2;issue=2;spage=70;epage=72;aulast=Rajpurohit, https://journals.sagepub.com/doi/abs/10.1177/0748233714545202?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=tiha, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682569/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202341/, https://www.sciencedirect.com/science/article/pii/S1931524415002224, https://fdc.nal.usda.gov/fdc-app.html#/food-details/601871/nutrients. Compared with those who took the placebo, those who consumed wheatgrass juice experienced: Learn more here about ulcerative colitis. Histamine Intolerance is a modern day Great Pretender. Sorry typo, Drs push MAny supplements of all kinds and. I havent tried it yet. My disease was triggered by a few things. If you havent already read our previous posts, you may want to check them out before reading on: Mast cells use an enzyme called histidine decarboxylase (HDC) to make histamine out of the amino acid histidine. https://content.amymyersmd.com/article/histamine-intolerance/. In addition, she is a wife, mother, and the successful founder and CEO ofAmy Myers MD . Other options include mixing it with milk, honey, or fruit juice. Eating a basic, anti-inflammatory diet to avoid common food sensitivities and additives is one of the first steps to take to repair your gut health. We dont 100% know the cause of this; I think a number of factors are involved. What are microgreens, what is their nutritional content, and what are their possible health benefits? We recommend against using pancreatic enzymes without a doctors recommendation. According to the authors, the proteins in wheatgrass can help prevent various diseases and oxidative stress, as well as help the body metabolize and store energy.. Then, reintroduce them one at a time by following my elimination diet guidelines. The current available DAO supplement is Umbrellux DAO. Benadryl may also decrease anxiety and increase serotonin in the brain, similar to SSRI antidepressants. Sorry for the book but I hope what I said was helpful. Fexofenadine (Allegra) is a drug that doesnt cause drowsiness because it doesnt cross the blood-brain barrier as efficiently as first-generation antihistamines like Benadryl (diphenhydramine) [80, 81, 79]. In pigs, however, carnosine inhibits diamine oxidase, which breaks histamine down in the gut. While a low histamine diet can feel strict, it will be worth it for the symptom management. It is literally my life saver. I just wanted to let people know that after reading this article, I suspected that I have MCAD as Ive had episodes of anaphylaxis and recently I began reacting to almost everything I ate. Check if ingredients like wheatgrass are histamine-friendly instantly with Fig. I might be okay a few days like this, but it wont be long before I break out into hives. ), Brain Gain w/berberine HCL et al (Cpn can cause AD as can other pathogens), ultimate Omega (3), Black seed (Cpn can cause Cancer). Common symptoms are: Once formed, histamine is either stored or broken down by an enzyme. People should only buy wheatgrass supplements from a trusted source, as most types of herbal medicine in the United States are not subject to quality control. These natural antihistamines include forskolin, quercetin, astragalus, vitamin C, and probiotics containing Bifidobacterium longum. Pneumoniae can invade mast cells! Our team thoroughly researches and evaluates the recommendations we make on our site. There are a number of factors that can contribute to, or cause, histamine intolerance, including excess histamine production, diamine oxidase (DAO) enzyme deficiency, HMNT mutation, and poor methylation in the liver; however, my experience has been that MCAD is responsible for a large number of cases of histamine intolerance. Find out here. The authors did not specifically test the histamine levels of the patients, but they compared the effect of the astragalus supplement to the effect of a non-sedating antihistamine and found them very similar [10]. All Rights reserved. Theanine is an amino acid found most abundantly in green and black tea and some fungi. I was diagnosed with SIBO in September, I believe PPI use caused this. Your email is safe with me. Researchers have found evidence that SIBO can cause autoimmune disease. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Its taken years for me, but slowly and surely I have found medications that work, supplements that work, and a routine that works. The website yeastinfectionadvisor.com has helped me understand about the biofilms that bacteria build around themselves to stop any antibiotics from killing them. In this article, learn more about the. S-adenosyl-L-methionine, also known as SAM-e, is a compound that naturally occurs in your body and which donates methyl groups during methylation processes. Order the test yourself. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. (18) Zinc is involved in regulating mast-cell function, and there may be a link between magnesium deficiency and inflammation. All physical exertion lands me in bed for three days. All rights reserved. As you consume more and more of these foods, the less your DAO enzymes will be able to keep your histamine intolerance symptoms in check. That is what I am currently working on is eroding the biofilm, and the Biofase is working, as long as I stay on a very restricted diet. When you sign up for my newsletter, youll get $10 OFF your next order in addition to my 56-page Guide to Leaky Gut eBook including everything you need to finally uncover the root cause of your conditions and overcome them. But in other cell-based studies, it increased histamine release; this may explain some of NACs side effects [72, 75, 76]. The researchers believe that the flavonoids and polyphenolic compounds in the plants methanol content may help prevent leukemia from developing in bone marrow cells. I am trying to find a DAO supplement, but currently it is hard to locate one. Other immune system chemicals complete the chain reaction to repair the damage to your tissues. Benadryl, an H1 receptor antagonist that also increases diamine oxidase (DAO) production, is better taken at night since it induces sleepiness. Were you able to get help? I have Fibromyalgia, Hashimotos, and extreme EHS (electrohypersensitivity) that sometimes puts me into complete paralysis. & sure makes sense ! He did say that I must stick with the low-hist diet, which I detest. People have used wheatgrass as a traditional medicine to treat type 2 diabetes, and some scientists have found evidence that it may help. Rheumatoid arthritis, type 1 diabetes, and psoriasis are all examples of autoimmune diseases. Always discuss new supplements with your doctor. Get my free newsletter, recipes, eBooks, product recommendations, and more! Histaminosis is the term used for any condition where the histamine level is far from the ideal range in the body, local or systemic. MCAD was not named as a condition until 2007 (10) and diagnostic criteria werent proposed until 2010. <>/Metadata 387 0 R/ViewerPreferences 388 0 R>> Thats cinches it. Reishi is a fan-shaped mushroom that is believed by some to enhance the immune response. It was the first time I heard mast cell disorder- and it led me to find out I have extra tryptase genes. The Low Histamine diet helps reduce symptoms from conditions like Histamine Intolerance (HIT) and Mast Cell Activation Syndrome (MCAS). If you wish to find out more about our editorial process and how we create content please enter here. I have joined a number of facebook groups regarding this condition. Do you have any ideas or a supplement that helps deal with histamine in the GI tract? You absolutely need to find a good mast cell doctor though. Histamine: Histamines are naturally occurring chemicals in foods like cheese, pineapples, bananas, avocados and chocolate. When you avoid hundreds of ingredients, grocery shopping is a challenge. Traditional medicinal uses of wheatgrass include: improving digestion lowering blood pressure removing heavy metals from the bloodstream balancing the immune system relieving gout While evidence. Ive come to the conclusion that every disease that Ive gotten is the result of the underlying mast cell problem not that the mast cell problem is caused by a disease. Pollen allergy symptoms include: runny nose, postnasal drip, watery eyes, red eyes, itchy eyes, a scratchy throat, nasal congestion and sneezing.include . No Zolair. DAO-blocking foods to avoid while following a histamine intolerance diet include: Alcohol SIBO (small intestinal bacterial overgrowth) can cause MCAS, and whatever caused SIBO in the first place can cause MCAS. I also have Sjogrens and I had my thyroid removed a year and a half ago. Most studies report no significant adverse effects after consuming wheatgrass, but this may depend on the form of the product and the individual. Mixing it with an ingredient that has a strong taste, such as pineapple, may make it more palatable. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Hair loss? Lead, cadmium, and bismuth have also been found to activate mast cells and cause mast cell mediator release. I wake up most mornings with histamine intolerance symptoms. Your email address will not be published. Ive been on Phenergan every night for the past 18 years because of food intolerances and had 4 anaphylactic reactions to Novocain at the Dentist. We provide sources to our claims and periodically update our content as new research develops. Forskolin is a compound extracted from a member of the mint family called Coleus forskohlii. While these may provide much-needed relief to patients, they are not a long-term solution and can have unwanted side effects. Bifidobacterium longum ssp. I have seen improvement in this area, yet MCAS is still an issue. From a physiological perspective, stress causes a surge in Cortisol and a surge in adrenaline. Instantly. Histamine can affect a number of organ systems which can then manifest through a number of symptoms. Research suggests that they may help to decrease the risk of heart disease and diabetes, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. However, this species more effectively degrades putrescine and tyramine [67]. A streamlined stack of supplements designed to meet your most critical needs -, getting enough sleep and avoiding blue light, Become a Functional Medicine Practitioner. A diet rich in fruits and vegetables is always the best choice, even if the wheatgrass research was more compelling. In the digestive tract, histamine is broken down by diamine oxidase (DAO).Though both enzymes play an important role in breaking down histamine, the American Society for Clinical Nutrition found that DAO is the main enzyme responsible.1 If youre deficient in DAO, you likely have symptoms of histamine intolerance symptoms. Palmitoylethanolamide, or PEA, is a fatty acid already found in your body. I write this as a suggestion for an alternative to those looking for an alternative to their current course of action. I do not experience anaphylaxis which is why I was unsure at first about MCAS being an accurate diagnosis. Metabolic syndrome usually starts with obesity. Many studies have produced promising results about the benefits of wheatgrass, but these have mostly been small studies. They found that the growth of cancer cells slowed down. Ive ordered some and hope to start within the next 2 weeks. Its notated on my bracelet to look in my purse. 5YwQ|Rxqo|H Every person has unique dietary triggers. Wheatgrass may improve overall mental function and relieve anxiety. High levels of oxidative stress can lead to various health problems, including cancer. Roughly 1% of the population has histamine intolerance; of those, 80% are middle-aged. A 2016 study on rats, for example, found that wheatgrass raised insulin levels and helped lower blood glucose. Brussels sprouts are low in calories and rich in protein. I also hate taking these antihistamines and am trying to find a natural approach like you, low histamine, all organic, cut out gluten and sugar. As far as the diet, Ive been gluten, dairy, sugar and additive free for a few years now. A high ratio of histamine to DAO signifies that you are ingesting too much histamine and that you dont have enough DAO to break it down. endobj These allergy-like symptoms can range from skin rashes to headaches, and you can manage them by avoiding histamine-rich foods and substances that activate your mast cells. Ive had so many members of my community tell me how Histazyme has provided them with the freedom of not having to worry about histamine intolerance when eating out. The cause of histamine intolerance is not yet fully understood. It stabilizes mast cells and suppresses inflammation in the lungs and nose, which makes it another good choice for asthma and seasonal allergies [30, 31, 32, 33]. From there, I could determine the underlying root cause. Arora, S., & Tandon, S. (2016). Antioxidants help fight chronic inflammation, which occurs when the immune system reacts to an unwanted substance. One glass of wine on its own isnt what brings me over the edge, its a glass of wine on top of everything else. (4) The key takeaway here is that we need mast cells and their mediators for normal body function. Id try the macrobiotic diet if I were you. (11). Test your individual tolerance to ingredients carefully and then keep track of them with the Fig app. The biggest risk from mast cell diseases is death from Anaphylaxis not the really annoying/painful symptoms. I am trying everything to get her help and figure out whats going on with her. tissue swelling. This makes sense, as the very purpose of using these as vaccine adjuvants is to elicit a heightened inflammatory immune response. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. They are not regulated or inspected for contents, fillers, Generally speaking, this vitamin is required for a healthy histamine metabolism. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. We shouldnt treat a piece of paper, we should treat people! My Dr. is Arye Rubenstein out of Einstein Medical College/Montefiore Medical Center. *If you have an autoimmune disease or are following The Myers Way, avoid all grains, legumes, and nuts until you are able to successfully reintroduce them to your histamine intolerance diet. MCAD is estimated to be more prevalent (9) than other diseases of mast cell dysfunction, but also more difficult to recognize. Medications That Cause Histamine Intolerance muscle relaxants pain medications Read on to find out. This worries me and Im not even sure it will address my main problems which are fatigue and brain fog along with the long list of other symptoms I have (I am disablility because I am so sick). For moral support there are quite a few good FB groups out there for MCAS or CIRS etcSending all the best to you, yours and all. My daughter is 7 years old. We cover an A to Z of popular healthy food items. My GI stated that my symptoms sound like Mast Cell Activation Syndrome. <>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 792 612] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Amy Myers, MD is a two-time New York Times bestselling author an an internationally acclaimed functional medicine physician.Dr. If you notice any of these conditions when you take medications, you should consult your doctor immediately. I had sky-high levels of it in the 24 hour urine test as well as high levels that fluctuated in three separrate blood plasma tests. And what triggers a response is unique to each person. Content on this website is not considered medical advice. Please see a physician before making any medical or lifestyle changes. Some flavored capsules are also available. There is not enough evidence to prove that wheatgrass can cure any disease. Would you share the herbs in your regime? One study indicated that it might have anticancer properties. Its a good choice if you suffer from allergies. DAO blockers (ingredients that block DAO, the enzyme that breaks down histamine and other amines) We've done our best to provide accurate information on the histamine content of wheatgrass; however, we suggest working with a dietitian to navigate the diet and understand your individual needs. For me I live in mold as well and cannot move. Mast cell activation disorder is characterized by the accumulation of mast cells that are genetically altered (mastocytosis) and/or the abnormal release of mast cell mediators (Mast Cell Activation Syndrome). Lisa I also have Mast cell issue and 2 immunologists recommended Zolair. Chris Kresser LLC, a Nevada LLC | 1810 E. Sahara Ave, Suite 402 Las Vegas, NV 89104 USA | 702.850.2599. J*+X("nI>s3IS{ZH,i>K3kWc{ ,,y"=N+6IMz1${%L|{zc!@f""K@,YH"Kpo"/[[x5Kd2NNv:1W@lxr Yasmina Ykelenstam encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.The content of this website and any provided materials, research, or communications are for informational purposes only. Elevated tryptase is a marker for Mastocytosis not MCAS. In rats, tulsi seed oil blocked histamine release from mast cells [62, 63, 64]. Mast cells are the sentinels of the innate immune system, on the lookout for environmental changes or insults to the body. Authors of a 2014 review suggested that wheatgrass may help treat ulcerative colitis, an inflammatory condition that affects the large intestine. Many have excellent results, a few do not. Heart failure: Could a low sodium diet sometimes do more harm than good? We have an appointment with an allergist in May, however Im so worried about the reactions shes having and dont know what to do in the meantime. Antihistamines. Foods high histamine (H), and highly perishable, rapid formation of histamine (H! S,b_^ZW=fO]:9?c+0+3n}]Yy/5]Njgx~fA/{vl{bf/tmz3>k}{_.Uplb#B9~xW`F05( ]oi\`fQe,{X/tbkkq:8n~mq.|INPU 7'5Fz$W@}8 Ughhh. I have never experienced anaphylaxis, fortunately. My concern is that some have indicated they feel their joints more and a few seem to have some hair loss. My diagnosis arose simply from my dermatographia and my positive response to cromolyn sodium. My pharmacy Stokes in NJ will also ship if you dont have a compound pharmacy near by. and may not be reproduced, resold, distributed, transmitted, displayed, published or broadcast except for the customer's personal use, without the prior written permission of Histamine, LLC dba Healing Histamine, Nearly every Blue Zone regions with the longest living people has moderate, daily alcohol consumption as part of its culture. I wouldnt have a meal without it! Those who are particularly susceptible to mold and have a reduced ability to clear mycotoxins from the body, which leads to a constant activation of mast cells. I can only take 60 mcg so I am hypothyroid. Cardiovascular health: Insomnia linked to greater risk of heart attack. In the central nervous system, histamine is mainly broken down by histamine N-methyltransferase (HMT). Erythropoietin (EPO) is a hormone that stimulates red blood cell production, also called erythropoiesis. Information is shared for educational purposes only. A histamine intolerance develops when the amount of histamine that accumulates in your body is greater than the amount of histamine your body can eliminate. This plants active compounds significantly reduced histamine release in rat studies [57, 58, 56]. What can I do to tackle this wretched illness and regain some quailty of life? Authors of a 2015 mouse study concluded that wheatgrass might help defend the body against leukemia, especially in those who are at risk due to benzene exposure. Ive had weird health problems for a long time. Histamine causes your blood vessels to swell so that your white blood cells can quickly move in to resolve any problems. I3C helping peanut allergies is interesting! %PDF-1.7 Our goal is to not have a single piece of inaccurate information on this website. I have recently been dignosed with Mast Cell Activation Syndrome by my immunologist in New York City. I am currently in need of taking DAO. I go to a concierge dr and hes been a lifesaver. Starting extremely low and titrating up. Following a low histamine diet helps tremendously, starting with intermittent fasting to get histamine levels down quickly. Seeking Health no longer makes Histame Block which was their DAO supplement. + Who Should Try It, Foods High & Low in Histamine + Other Mast Cell Triggers, You can read our list of natural ways to increase EPO here. So I got off gluten, but that led me to arsenic laden brown rice products. Do this by eating a low-histamine diet and avoiding foods that block DAO. Those struggling with candida ( here's how histamine makes yeast infections even nastier) or small intestinal bacterial overgrowth (SIBO) will obviously want to avoid it. Your reaction to wheatgrass may be different than someone else's. Read on to learn more about MCAD, and how you can address the root cause. % Wheat germ DAO-Blocking Foods Some foods and drinks interfere with your body's natural balance of HMT and DAO enzymes. Join our community and get tips on health, wellness, nutrition, and more. However, people with celiac disease, and those who are sensitive to gluten can still enjoy wheatgrass because only the wheat kernel and not wheatgrass contains gluten. endobj Parit, S. B. My weight started dropping dramatically because I was too scared to eat because of the pain. I have like an allergic reaction to wireless frequencies. Modern life is making you sick to your stomach. However, I strongly feel that I could have MCAS but dont know if a local doctor can accurately diagnose me with this. In fact, it is also sometimes used as an occasional sleep aid [83, 84]. It stabilizes mast cells, reduces inflammation, and strengthens blood vessels [7, 42, 43, 44]. 8816 Cullen Ln, Austin, TX 78748, 2016-2023 AMMD, LLC (AmyMyersMD.com). You may want to talk to your doctor about whether you might be deficient in B6 [11, 66]. Well once I figured this out I realized all thyroid pills have confectioners sugar (my trigger). This means you can take it before meals, 2-3 times a day to help break down histamine in the gut. The entire contents of this website are based upon the opinions of Yasmina Ykelenstam, unless otherwise noted. endobj N-acetyl cysteine (NAC) is an amino acid supplement and a strong antioxidant. The Low Histamine diet helps reduce symptoms from conditions like Histamine Intolerance (HIT) and Mast Cell Activation Syndrome (MCAS). I was skeptical but willing to try anything for relief. Besides stabilizing mast cells, EGCG has the added benefit of reducing the number of mast cells present at any time [36, 37]. Dont know if you found the answers to your questions or not but yes you probably have MCAS. Avoiding yeast In baking, bicarbonate of soda and sometimes calcium carbonate, are great substitutes. You may have gotten here from one of our previous articles on histamine intolerance. did not work. The roots of the Chinese skullcap, a plant from the mint family, are important in traditional Chinese medicine. 3 Powerful Supplements For Histamine Intolerance. Mitochondrial pathway mediated apoptosis and cell cycle arrest triggered by aqueous extract of wheatgrass in colon cancer colo-205 cells [Abstract]. many brands of turmeric, or other herbals, and even vitamins were found to contain corn meal(GMO type). Xanthine occurs naturally in the human body, while the methylxanthines, which stabilize mast cells, are under investigation as potential asthma treatments. Wheatgrass is also available in capsule form, which almost eliminates the taste. I fit the vast symptoms of the disorder. SelfDecode does not treat, diagnose or cure any conditions, Its quite difficult though to get Bifidobacterium infantis separately as an individual strain, without other strains that are also in it. Click here to learn about her. My blood work in August indicated an ANA positive result, high red blood cell count, high lymphocyte and monocyte, and low granulocyte. Have you struggled to get a diagnosis? Those meds in addition to an anti-inflammatory diet keep me out of Anaphylaxis which is great because I dont want to die. Hives and itchy skin. Turns out one of my primary triggers for my mast cell is anything in the CANE family so mostly sugar and any cane sugar derivative and also coconut.